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About AbbVie

AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world.  For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook or LinkedIn.​

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Senior Scientist II / Principal Scientist I, Process Chemistry

Research & Development
2000734 Requisition #
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Following its separation from Abbott, AbbVie formed in 2013 and combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader. AbbVie employs approximately 29,000 people worldwide and markets medicines in more than 170 countries.


AbbVie is seeking a Senior Scientist II / Principal Scientist I to conduct process research and development of small molecules from pre-clinical through commercialization. We seek a highly motivated scientist, with a proven track record of accomplishment in the biopharmaceutical industry, to work in a multi-functional team environment. The qualified candidate will deliver results in a team-oriented setting.


Key Responsibilities:


  • The successful candidate will be responsible for setting project strategies, defining project responsibilities and timelines, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing of AbbVie’s small molecule and/or antibody-drug conjugate candidates.
  • Conceive of and develop synthetic routes for early-stage clinical deliveries, demonstrate processes in the API Pilot Plant, develop commercial manufacturing processes, establish commercial control strategies, and transfer the processes to commercial manufacturing sites.
  • The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, solid state scientists, drug product development, program management, etc.  The selected candidate will collaborate with Asset Development Teams to advance clinical candidates. It is expected that the candidate will utilize his/her expertise across CMC disciplines to generate collaborations with drug product development, regulatory affairs, and commercial operations, to further program goals.
  • Serve as the lead author on development reports and as a key contributor to regulatory filings.

  • BS, MS, or PhD in chemistry and 12-14 (BS), 10-12 (MS), or 4-6 years (PhD) of relevant experience required. Candidates with less experience may be considered for other opportunities.
  • Proven scientific leadership and a demonstrated ability to lead cross-functional process development teams in a collaborative fashion.
  • The successful candidate will have a strong understanding of control strategy development, regulatory starting material strategies, specification setting, determining operating parameter ranges, QbD principles and process validation requirements.
  • An understanding of global regulatory expectations and experience with authoring development reports and regulatory filings is highly desirable.
  • The ideal candidate will have strong verbal and written communication skills

Key Leadership Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.

  • Learns fast, grasps the "essence" and can change course quickly where indicated.

  • Raises the bar and is never satisfied with the status quo.

  • Creates a learning environment, open to suggestions and experimentation for improvement.

  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Level and compensation will be commensurate with experience

Equal Employment Opportunity Employer

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients.  As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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