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About AbbVie

AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world.  For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook or LinkedIn.​

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Senior Scientist I/II, Bioinformatics, Neuroscience

Research & Development
2000584 Requisition #
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The Genomics Research Center (GRC) is a center of excellence for bioinformatics, functional genomics, human genetics, pharmacogenomics and multiple population cohorts (over 1 million genomes) and works across all R&D, and other areas such as process sciences and corporate strategy. The GRC plays an integral role towards our goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials.  Within the GRC, the Department of Computational Biology drives research by data analysis and data integration for activities such as the identification and validation of new targets, elucidating underlying biological mechanisms for disease development and progression, translational research, and patient stratification. 

AbbVie’s Neuroscience R&D seeks novel therapeutic approaches that will have a remarkable impact on patients with neurodegenerative diseases. The focus areas are Alzheimer’s and Parkinson’s disease, but includes other adjacent disorders such as multiple sclerosis and stroke. 

We have an exciting opportunity for a Computational Biologist/ Bioinformatician, based in Cambridge, MA embedded in Neuroscience. The successful candidate will work closely with bioinformatics and wet-lab groups in Cambridge (MA), Ludwigshafen (Germany) and North Chicago (IL) to contribute to target and biomarker identification, validation and project advancement by OMICS data analysis.

Key Responsibilities: 
  • Develop strategies for and perform integrated analysis of high dimensional OMICS data such as genomics, transcriptomics, proteomics and metabolomics in the context of early stage drug discovery for neurological diseases especially Alzheimer’s Disease and Parkinson’s Disease.
  • Support identification of potential new drug targets and biomarkers by analysis of data from consortia, preclinical models and clinical studie
  • Evaluation, development and implementation of computational methods, pipelines and tools for data analysis and visualization.
  • Work in close collaboration with disease biology experts, statisticians and bioinformaticians within AbbVie. Objectives, strategies and results are discussed in interdisciplinary teams. 

Position will be hired based on level of experience. 
  • Bachelors, Masters or PhD in Bioinformatics, (Bio)Statistics, (Bio)Mathematics, Genetic Epidemiology or Biology/Medicines related disciplines with a strong focus on data analysis with typically 10-12+ (BS), 8-10+ (MS), 0-4+ (PhD) years of experience
  • 5-10 years’ experience in hands-on analysis of OMICS data, especially transcriptomics and proteomics, ideally experience with single cell RNAseq. 
  • Expertise and experience in basic Neuroscience research and/or Neuroscience drug discovery.
  • Fluency in one or more relevant programming languages, such as R or Python.
  • Fluent in English.
  • Very good communication skills demonstrated in inter-disciplinary teams.

Equal Employment Opportunity Employer

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients.  As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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