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About AbbVie

AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world.  For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook or LinkedIn.​

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Senior Scientist I, Bioinformatics

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Research & Development
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1908493 Requisition #
Join our Talent Community

The Genomics Research Center (GRC) is a center of excellence for bioinformatics, functional genomics, human genetics, pharmacogenomics and multiple population cohorts (over 1 million genomes) and works across all R&D, and other areas such as process sciences and corporate strategy. The GRC plays an integral role towards our goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials.

 

Within the GRC, the Department of Computational Biology drives research by data analysis and data integration with Discovery and Development in activities such as the identification and validation of new targets, elucidating underlying biological mechanisms for disease development and progression, translational research, and patient stratification.

 

 

 

We have an exciting opportunity for a Senior Scientist based in North Chicago, IL. This role involves the identification and characterization of underlying genetic, epigenetic, or genomic factors that are associated with disease diagnosis, prognosis and response (efficacy and safety) to new drug treatment.

 

 

 

 

 

Key Responsibilities:

 

  • Devise and execute sophisticated analyses to extract meaningful and actionable information from various omics (e.g. genomic, transcriptomic, epigenomic, proteomic) data from clinical / translational activities with a focus on Immunology Development at AbbVie, as well as from relevant external studies.

  • Primarily collaborate with pharmacogenomics / translational science in Immunology to contribute to studies related to drug response, biomarkers, or disease etiology and progression, with focus on the computational aspects of the projects.

  • Perform necessary quality control checks and data management of large omics data and phenotypic datasets.

  • Review and contribute to the establishment of relevant pipelines, workflows, and underlying methodology.

  • Communicate analytical results verbally and in writing for scientific and technical

 

 

Basic requirements:

  • PhD or other advanced degree in computational biology, bioinformatics, computer science, engineering, statistics, epidemiology, mathematics, or related fields.
  • Fluency in 1 or more relevant programming languages such as R, Python, Perl, Java, or C++, and be comfortable working in a HPC Linux environment.
  • Experience with large-scale data analysis involving the integration of next generation sequencing data.
  • Demonstrated ability to develop and execute custom computational analysis plan leveraging novel algorithms and relevant databases.
  • Hands-on experience in genomics, genetic and/or epigenetic data analyses using existing and custom pipelines.
  • Strong communication skills, innate scientific curiosity and collaborative team spirit.
  • Ability to summarize analytical results and derive biological/clinical interpretation.

 

Preferred qualifications:

  • Working experience in biopharma industry.
  • Experience in translating genomic data into clinically relevant results.
  • Experience with large-scale research projects involving multi-omic data, such as whole exome and whole genome sequencing data, array-based genotype data, RNA-seq data, array-based expression data, methylome data, and neuroimaging data.
  • Fluency with clinical trials and translational studies.

Equal Employment Opportunity Employer

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients.  As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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