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About AbbVie

AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world.  For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook or LinkedIn.​

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Lab Leader/Senior Scientist Drug Transport and Absorption (m/f/d)

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Research & Development
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1900819 Requisition #
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The role: 

The Lab Leader/Senior Scientist position is situated in the Drug Metabolism and Disposition group of the Drug Metabolism and Pharmacokinetics-Bioanalysis (DMPK-BA) department in Ludwigshafen, Germany. The mission of the group is to analyze the ADME (Absorption, Distribution, Metabolism and Excretion) properties and pharmacokinetics of small molecules and biologics to support the discovery pipeline. The successful candidate will have the following responsibilities: 
  • You supervise a team of 3-4 experienced associates, and develop internal/external collaborations to overcome capacity or capability challenges
  • You are responsible for the excellence center of efflux transporters in Ludwigshafen within the global AbbVie organization and you conduct all efflux studies from early screening to IND/NDA applications and post-marketing.
  • You ensure quality and timely execution of all studies in a cost efficient manner, design and conduct novel and innovative  assays to address specific scientific or regulatory questions, and you are the subject matter expert within the global DMPK-BA organization for this activity.
  • You will establish an excellence center for absorption. You will apply, explore and develop new in vitro approaches and collaborate closely with formulation scientists and PBPK (physiologically-based pharmacokinetics) modelers to enhance the prediction of oral absorption for new chemical entities. You will expand the current capabilities to understand/predict oral absorption or subcutaneous absorption of new modalities beyond drug-like small-molecules.
  • You will function as key point of contact for this activity within the global DMPK-BA organization.
Your AbbVie Talent: 
  • You hold a PhD in biochemistry, biology or related field with at least 5 years of experience in the pharmaceutical industry or in a CRO as an expert of drug transporter / drug absorption (especially for cell-based assays) with a proven track record (e.g. relevant publications, posters, speaker at international conferences).
  • Optionally, you have experience with LC-MS/MS analytics, lab automation, and/or HPLC with radio-detection.
  • You possess excellent teamworking skills and a high degree of self-initiative, as the role is highly interdisciplinary within the AbbVie organization.
  • You have excellent presentation and negotiation skills and ideally already have some experience as a DMPK project representative within research and development projects in a pharma context.
We offer you: 
  • A challenging job with high personal responsibility in a committed and competent team. Your mentoring will be accompanied by a mentor who will assist you as coach and contact person.
  • We create the ideal environment for focused and passionate work, providing our employees with the utmost flexibility to tailor their daily work to their individual needs, including flexible work models, multiple benefits, and comprehensive health and sports programs.
  • Attractive compensation and company benefits, including our excellent occupational health management system, which is one of the best in Germany as well as a wide range of career paths and opportunities for further development.
We are looking forward to  your application. Please provide information about your salary expectations and possible start date in your motivation letter.
 
An equal opportunity employer. AbbVie welcomes and encourages diversity in our workforce.
 
Learn more about AbbVie Deutschland at www.abbvie.de. Visit www.abbvie-care.de for more information about the therapeutic areas in which we’re active.

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